Vignatex combines two powerful vitexin and isovitexin rich extracts from mung bean and passion flower. Mung bean produces powerful inflammation and oxidation regulating effects, paired with a strong undercurrent of stimulation. The stimulation is mostly coming from monoamine oxidase B inhibition (MAO-B), an enzyme which normally degrades dopamine and norepinephrine. When MAO-B is inhibited, dopamine and norepinephrine levels go up, which leads to focus, motivation and energy enhancing effects. Taken alone, this effect can be somewhat unbalanced, but when paired with passionflower, the effects are smoothed out slightly, leading to a very unique flow state like stimulating effect.
While the mood elevating and focus enhancing effects are highlights of vignatex, the pain management effects are also very unique and prominent. This positions vignatex as one of the more unique pain management supplements we offer, as it helps give you back the energy that pain can rob you from, while simultaneously promoting pain management!
Vignatex is a unique combination of Vigna radiata, better known as mung bean, and Passiflora incarnata, better known as passion flower. These plants are both high in two unique flavones, vitexin and isovitexin. These flavones, interestingly enough, are actually the glycosides of apigenin, with vitexin being apigenin-8-C-glucoside and isovitexin being apigenin-6-C-glucoside.
The mung bean extract that is being used is standardized to a whopping 10% vitexin and 10% isovitexin. While the passionflower extract is not standardized to a vitexin or isovitexin content, passionflower does contain significant levels of vitexin and isovitexin and we pick our passionflower extract based on subjective effects discovered during painstaking bioassaying.
The mung bean portion of Vignatex has a stimulating effect, while the passionflower portion of vignatex reinforces the stimulating effects while also smoothing it out and bringing relaxing effects to the mix. The end result is a wonderfully focused and mood boosting stack, which also has a lot of benefits for cytokine levels and pain management! What we love most about vignatex, is that it produces a pleasant relaxing effect throughout the body, which makes your muscles feel more limber and joints more comfortable!
For a long time, we were searching for a natural inhibitor of monoamine oxidase B (MAO-B) that also had pleasant overall effects. This took quite a while, but eventually we discovered that isovitexin could pull this trick off quite well! Next up, we had to find a source of isovitexin and quickly discovered that a culinary bean, mung beans, contained large quantities of both isovitexin and vitexin. Once we sourced a high vitexin and isovitexin extract, we bioassayed it, and were shocked by the powerful effects we received. Not only did we achieve the nootropic MAO-B inhibitor effects profile we were looking for, we also discovered significant pain management benefits!
However, by itself, the mung bean felt a little bit unbalanced, leaning a little bit too much into “edgy” territory. We needed to figure out a way to temper mung beans effects profile, while also keeping the focus on vitexin and isovitexin. To our surprise, we discovered that passionflower also contains vitexin and isovitexin, and due to the fact that passionflower has a calming effect, we could now keep the focus on vitexin and isovitexin while reeling their effects in a little bit. This did not turn out to be an easy task! Certain passion flower extracts actually further increased the stimulating effects of the mung bean extract. Ten or so bioassaying sessions later, we finally found the perfect passion flower extract. It took the edge off of the mungbean extract, and further increased the mood boosting properties of mung bean. Once we got the ratios right, vignatex was born, which displayed, in our opinions, a wonderful balance of effects! You may also be asking yourself, why the name vignatex? This is based on the botanical name for mung bean Vigna radiata, and (iso)vitexin. Combine the two, and you’ve got Vignatex!
MAO-B is an enzyme which normally degrades dopamine and norepinephrine, and thus when MAO-B is blocked by vignatex, both dopamine and norepinephrine levels increase. For most, this is subjectively experienced as a clean stimulating nootropic effect with a pleasant uplifting mood boost. Inhibition of MAO-B can also exert neuroprotective effects, mostly by preventing the creation of dopamine metabolites which are strong oxidants. When the MAO-B style stimulation is tempered by the mild GABAergic effects of passionflower, the effects become quite smooth, making it easy to attain “flow state” like focus!
Vignatex also does a fantastic job of mitigating pain via its powerful inflammation, oxidation and cytokine regulating effects. Vitexin also has another trick up its sleeve, it can actually modulate neurological pain signaling by interacting with the TRPV1 receptor, which is the same receptor where capsaicin can exert its pain modulating effects. Taken together, all of these mechanisms add up to a profound pain management effect. This pain management effect also goes great with the MAO-B inhibition effects. Oftentimes, experiencing pain can make us feel dull, tired and unfocused. By targeting both the root cause of the pain with vignatex, while providing stimulating nootropic effects, vignatex helps tackle both the physical and mental effects of pain!
As a dietary supplement, take one capsule of Vignatex daily.
To gain more insight, see the Vignatex reviews and experiences below.
Natrium Health offers 60ct. or 120ct. jars of high-quality Vignatex. Natrium Health’s Vignatex has been lab-tested and verified for both product purity and identity.
Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.